Relative Potencies and Equivalent Doses of Corticosteroids
|
RELATIVE POTENCIES AND EQUIVALENT DOSES OF CORTICOSTEROIDS |
|
Glucocorticoid |
Approx. Equiv. Dose* Potency |
Relative Anti-Inflam.
Potency |
Relative Sodium Retaining |
Duration
of Action T 1/2 (hrs) |
|
Short-acting (S) |
|
|
|
|
|
Cortisone |
25 |
0.8 |
0.8 |
8-12 |
|
Hydrocortisone |
20 |
1 |
1 |
8-12 |
|
Intermediate-acting
(I) |
|
|
|
|
|
Prednisone |
5 |
4 |
0.8 |
12-36 |
|
Prednisolone |
5 |
4 |
0.8 |
12-36 |
|
Methylprednisolone |
4 |
5 |
0.5 |
12-36 |
|
Triamcinolone |
4 |
5 |
0 |
12-36 |
|
Long-acting (L) |
|
|
|
|
|
Betamethasone |
0.6 |
30 |
0 |
36-54 |
|
Dexamethasone |
0.6 |
25 |
0 |
36-54 |
|
*These dose
relationships apply only to oral or intravenous administration; relative
potencies may differ greatly when injected intramuscularly into joint spaces. |