Vinblastine; Vincristine; Vinorelbine

IV Use Only; Granulocytopenia; Avoid Extravasation

Intravenous Use Only

  • Experienced Physician
  • Intrathecal use of other vinca alkaloids has been fatal.
  • Label syringe "WARNING-FOR IV USE ONLY, FATAL if given intrathecally

Granulocytopenia

  • May be severe and predispose to infection

Avoid Extravasation

  • Proper placement of needle/catheter prior to administration

Monitoring data

  • Granulocyte counts should be > 1000 cells/mm3 prior to administration
  • Adjust dosage according to complete blood cell counts/differentials(taken on day of administration)